Last modified: Jan 30, 2026 By Alexander Williams

ChatGPT Python API Guide for Beginners

Artificial intelligence is changing software. The ChatGPT API puts this power in your hands. You can use it with Python.

This guide will show you how. We will start from the very beginning. You will learn to make your first AI-powered application.

What is the ChatGPT Python API?

The ChatGPT API is a service from OpenAI. It lets your Python code talk to their AI models. You send text, and it sends back intelligent responses.

Think of it as a super-smart assistant for your programs. You can build chatbots, content generators, and analysis tools. The possibilities are vast.

It works over HTTP, just like any other web service. The official openai Python library makes it simple to use.

Getting Started: Setup and Installation

First, you need an OpenAI account. Go to their platform website and sign up. Then, navigate to the API keys section.

Create a new secret key. Save it immediately. You will not see it again. This key is your password to the API.

Next, install the OpenAI Python library. Use pip, the Python package manager. Open your terminal or command prompt.


pip install openai
    

Now, you are ready to write code. Always keep your API key secure. Never share it or commit it to public code repositories.

Making Your First API Call

Let's write a simple script. It will ask ChatGPT a question and print the answer. We start by importing the library and setting the key.

Use the openai.ChatCompletion.create() method. This is the main function for interacting with the chat models.


import openai

# Set your API key
openai.api_key = "your-secret-api-key-here"

# Define the conversation
response = openai.ChatCompletion.create(
    model="gpt-3.5-turbo",
    messages=[
        {"role": "user", "content": "Explain quantum computing in one sentence."}
    ]
)

# Print the AI's reply
print(response.choices[0].message.content)
    

Run this script. You should see a concise explanation of quantum computing. Congratulations! You've just used the ChatGPT API.

The model parameter chooses which AI to use. "gpt-3.5-turbo" is fast and cost-effective. "gpt-4" is more capable but slower.

The messages parameter is a list of conversation turns. Each turn has a "role" (like "user" or "assistant") and "content".

Understanding the Response Structure

The API returns a complex JSON object. The openai library converts it to a Python dictionary. You need to know how to extract the text.

The main path is: response['choices'][0]['message']['content']. Let's break down a sample output.


Quantum computing uses quantum-mechanical phenomena to perform calculations far more efficiently than classical computers for certain problems.
    

The response object contains other useful data. You can find the token count, model used, and finish reason. This is helpful for logging and debugging.

Understanding API responses is a key skill. It applies to many services, like when you're pulling data from other sources. For a broader foundation, see our Python API Data Pulling Guide.

Building a Conversational Chatbot

A single question is useful. But real chatbots have memory. They remember what was said earlier. You can build this by managing the message history.

Each API call must include the full conversation history. The model has no memory between calls. You must send all previous messages.


import openai

openai.api_key = "your-secret-api-key-here"

# Start a conversation history
conversation_history = [
    {"role": "system", "content": "You are a helpful coding assistant."},
    {"role": "user", "content": "How do I write a for loop in Python?"}
]

# First call
response = openai.ChatCompletion.create(
    model="gpt-3.5-turbo",
    messages=conversation_history
)

ai_reply = response.choices[0].message.content
print("AI:", ai_reply)

# Add AI's reply to history
conversation_history.append({"role": "assistant", "content": ai_reply})

# User asks a follow-up question
conversation_history.append({"role": "user", "content": "Can you show an example with a list?"})

# Second call with full history
response = openai.ChatCompletion.create(
    model="gpt-3.5-turbo",
    messages=conversation_history
)

print("AI:", response.choices[0].message.content)
    

The system message sets the AI's behavior. It is a powerful tool for guiding the assistant's tone and expertise.

By appending each response to the list, you create context. The AI can now refer back to the earlier question about for loops.

Advanced Parameters for Control

The basic call works well. For more control, use advanced parameters. They let you fine-tune the AI's creativity and response length.

  • max_tokens: Limits the length of the response.
  • temperature: Controls randomness. 0 is deterministic, 1 is creative.
  • top_p: An alternative to temperature for nucleus sampling.
  • stream: Get responses in real-time chunks.

response = openai.ChatCompletion.create(
    model="gpt-3.5-turbo",
    messages=[{"role": "user", "content": "Write a short poem about Python."}],
    max_tokens=50,
    temperature=0.7,  # A bit creative
    top_p=0.9
)
print(response.choices[0].message.content)
    

Experiment with these settings. A lower temperature is good for factual answers. A higher temperature is better for stories and ideas.

Handling different data types, including numbers, is crucial in API work. Learn more in our dedicated Python API Number Handling Guide.

Handling Errors and Best Practices

APIs can fail. Your code should handle errors gracefully. Common issues include invalid keys, rate limits, and server errors.

Use try-except blocks. The OpenAI library raises specific exceptions. Always implement a plan for when the API is unavailable.


import openai
from openai.error import AuthenticationError, RateLimitError

openai.api_key = "your-key"

try:
    response = openai.ChatCompletion.create(
        model="gpt-3.5-turbo",
        messages=[{"role": "user", "content": "Hello"}]
    )
    print(response.choices[0].message.content)
except AuthenticationError:
    print("Error: Invalid API key. Please check your key.")
except RateLimitError:
    print("Error: You have hit the rate limit. Please wait a moment.")
except Exception as e:
    print(f"An unexpected error occurred: {e}")
    

Best practices are key. Always use environment variables for your API key.